3K75
X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain
Summary for 3K75
Entry DOI | 10.2210/pdb3k75/pdb |
Related | 3K76 3K77 |
Descriptor | DNA repair protein XRCC1, DNA polymerase beta (2 entities in total) |
Functional Keywords | allosteric disulfide, xrcc1, pol beta, dna damage, dna repair, nucleus, phosphoprotein, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, methylation, nucleotidyltransferase, transferase, dna-binding protein, dna binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus: P18887 P06766 |
Total number of polymer chains | 4 |
Total formula weight | 100793.28 |
Authors | Cuneo, M.J.,London, R.E. (deposition date: 2009-10-12, release date: 2010-04-28, Last modification date: 2024-02-21) |
Primary citation | Cuneo, M.J.,London, R.E. Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity. Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010 Cited by PubMed: 20351257DOI: 10.1073/pnas.0914077107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.95 Å) |
Structure validation
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