3K75

X-ray crystal structure of reduced XRCC1 bound to DNA pol beta catalytic domain

3K75 の概要

• エントリーDOI: 10.2210/pdb3k75/pdb
• 関連するPDBエントリー: 3K76 3K77
• 分子名称: DNA repair protein XRCC1, DNA polymerase beta (2 entities in total)
• 機能のキーワード: allosteric disulfide, xrcc1, pol beta, dna damage, dna repair, nucleus, phosphoprotein, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, methylation, nucleotidyltransferase, transferase, dna-binding protein, dna binding protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Nucleus: P18887 P06766
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 100793.28

構造登録者

Cuneo, M.J.,London, R.E. (登録日: 2009-10-12, 公開日: 2010-04-28, 最終更新日: 2024-02-21)

• 主引用文献: Cuneo, M.J.,London, R.E.; Oxidation state of the XRCC1 N-terminal domain regulates DNA polymerase beta binding affinity.; Proc.Natl.Acad.Sci.USA, 107:6805-6810, 2010; PubMed: 20351257; DOI: 10.1073/pnas.0914077107

実験手法

X-RAY DIFFRACTION (2.95 Å)