3K4S

The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone

3K4S の概要

• エントリーDOI: 10.2210/pdb3k4s/pdb
• 関連するPDBエントリー: 3IAK
• 分子名称: cAMP-specific 3',5'-cyclic phosphodiesterase 4D, ZINC ION, (4R)-4-(3-butoxy-4-methoxybenzyl)imidazolidin-2-one, ... (5 entities in total)
• 機能のキーワード: nucleotide binding, phosphodiesterase, alternative splicing, camp, cytoplasm, cytoskeleton, hydrolase, membrane, metal-binding, phosphoprotein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Cytoplasm (By similarity): Q08499
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 40464.42

構造登録者

Crawley, L.,Cheng, R.K.Y.,Wood, M.,Barker, J.,Felicetti, B.,Whittaker, M. (登録日: 2009-10-06, 公開日: 2009-10-20, 最終更新日: 2023-09-06)

• 主引用文献: Crawley, L.,Cheng, R.K.Y.,Wood, M.,Barker, J.,Felicetti, B.,Whittaker, M.; The structure of the catalytic domain of human PDE4d with 4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone; To be Published,

実験手法

X-RAY DIFFRACTION (2.05 Å)