3K4A

Crystal structure of selenomethionine substituted E. coli beta-glucuronidase

Summary for 3K4A

Entry DOI	10.2210/pdb3k4a/pdb
Related	3K46 3K4D
Descriptor	Beta-glucuronidase (2 entities in total)
Functional Keywords	alpha/beta barrel, sugar-binding domain, beta-sandwich domain, glycosyl hydrolase, glycosidase, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	2
Total formula weight	138769.31
Authors	Wallace, B.D.,Orans, J.,Redinbo, M.R. (deposition date: 2009-10-05, release date: 2010-11-17, Last modification date: 2017-11-01)
Primary citation	Wallace, B.D.,Wang, H.,Lane, K.T.,Scott, J.E.,Orans, J.,Koo, J.S.,Venkatesh, M.,Jobin, C.,Yeh, L.A.,Mani, S.,Redinbo, M.R. Alleviating cancer drug toxicity by inhibiting a bacterial enzyme. Science, 330:831-835, 2010 Cited by PubMed: 21051639 DOI: 10.1126/science.1191175 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation