3K36

Crystal Structure of B/Perth Neuraminidase

3K36 の概要

• エントリーDOI: 10.2210/pdb3k36/pdb
• 関連するPDBエントリー: 3K37 3K38 3K39 3K3A
• 分子名称: Neuraminidase, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (7 entities in total)
• 機能のキーワード: influenza, neuraminidase, mutation, resistance, hydrolase, cell membrane, glycosidase, membrane, transmembrane, virion
• 由来する生物種: Influenza B virus (Viruses)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 90560.39

構造登録者

Oakley, A.J.,McKimm-Breschkin, J.L. (登録日: 2009-10-02, 公開日: 2010-09-01, 最終更新日: 2023-11-01)

• 主引用文献: Oakley, A.J.,Barrett, S.,Peat, T.S.,Newman, J.,Streltsov, V.A.,Waddington, L.,Saito, T.,Tashiro, M.,McKimm-Breschkin, J.L.; Structural and Functional Basis of Resistance to Neuraminidase Inhibitors of Influenza B Viruses.; J.Med.Chem., 2010; PubMed: 20695427; DOI: 10.1021/jm100621s

実験手法

X-RAY DIFFRACTION (2.2 Å)