3K26

Complex structure of EED and trimethylated H3K4

3K26 の概要

• エントリーDOI: 10.2210/pdb3k26/pdb
• 関連するPDBエントリー: 3JPX 3JZG 3JZH 3JZN 3K27
• 分子名称: Polycomb protein EED, HISTONE PEPTIDE (3 entities in total)
• 機能のキーワード: wd40, structural genomics, nppsfa, national project on protein structural and functional analysis, structural genomics consortium, sgc, alternative initiation, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation, national project on protein structural and functional analyses
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Nucleus: O75530
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43721.89

構造登録者

Bian, C.B.,Xu, C.,Qiu, W.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (登録日: 2009-09-29, 公開日: 2009-12-15, 最終更新日: 2011-07-13)

• 主引用文献: Xu, C.,Bian, C.,Yang, W.,Galka, M.,Ouyang, H.,Chen, C.,Qiu, W.,Liu, H.,Jones, A.E.,Mackenzie, F.,Pan, P.,Li, S.S.,Wang, H.,Min, J.; Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2).; Proc.Natl.Acad.Sci.USA, 107:19266-19271, 2010; PubMed: 20974918; DOI: 10.1073/pnas.1008937107

実験手法

X-RAY DIFFRACTION (1.58 Å)