3JZG
Structure of EED in complex with H3K27me3
Summary for 3JZG
Entry DOI | 10.2210/pdb3jzg/pdb |
Related | 3JPX 3JZH 3JZN 3K26 3K27 |
Descriptor | Polycomb protein EED, HISTONE PEPTIDE (3 entities in total) |
Functional Keywords | wd40, structural genomics, human, structural genomics consortium, sgc, alternative initiation, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: O75530 |
Total number of polymer chains | 2 |
Total formula weight | 46662.97 |
Authors | Xu, C.,Bian, C.B.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Min, J.,Structural Genomics Consortium (SGC) (deposition date: 2009-09-23, release date: 2009-12-15, Last modification date: 2011-07-13) |
Primary citation | Xu, C.,Bian, C.,Yang, W.,Galka, M.,Ouyang, H.,Chen, C.,Qiu, W.,Liu, H.,Jones, A.E.,Mackenzie, F.,Pan, P.,Li, S.S.,Wang, H.,Min, J. Binding of different histone marks differentially regulates the activity and specificity of polycomb repressive complex 2 (PRC2). Proc.Natl.Acad.Sci.USA, 107:19266-19271, 2010 Cited by PubMed: 20974918DOI: 10.1073/pnas.1008937107 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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