3JZG

Structure of EED in complex with H3K27me3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001222	molecular_function	transcription corepressor binding
A	0003682	molecular_function	chromatin binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005694	cellular_component	chromosome
A	0005829	cellular_component	cytosol
A	0006325	biological_process	chromatin organization
A	0008047	molecular_function	enzyme activator activity
A	0021510	biological_process	spinal cord development
A	0031491	molecular_function	nucleosome binding
A	0031507	biological_process	heterochromatin formation
A	0035098	cellular_component	ESC/E(Z) complex
A	0042054	molecular_function	histone methyltransferase activity
A	0042802	molecular_function	identical protein binding
A	0045892	biological_process	negative regulation of DNA-templated transcription

Functional Information from PROSITE/UniProt

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSVskDhALRLWNI

Chain	Residue	Details
A	LEU206-ILE220

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	THR55

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:20974918

Chain	Residue	Details
A	LYS66
A	LYS197
A	LYS268
A	LYS284

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