3JXT

Crystal structure of the third PDZ domain of SAP-102 in complex with a fluorogenic peptide-based ligand

3JXT の概要

• エントリーDOI: 10.2210/pdb3jxt/pdb
• 分子名称: Disks large homolog 3, Voltage-dependent calcium channel gamma-2 subunit, ACETATE ION, ... (4 entities in total)
• 機能のキーワード: sap102, dlg3, stargazin, 4-dmap, 4db, pdz domain, solvatochromic flurophore, fluorogenic probe, calcium channel, calcium transport, ion transport, ionic channel, transport, voltage-gated channel, signaling protein
• 由来する生物種: Rattus norvegicus (rat); 詳細
• 細胞内の位置: Membrane; Multi-pass membrane protein: O88602
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 24095.75

構造登録者

Sainlos, M.,Olivier, N.B.,Imperiali, B. (登録日: 2009-09-21, 公開日: 2010-09-29, 最終更新日: 2023-11-22)

• 主引用文献: Sainlos, M.,Iskenderian-Epps, W.S.,Olivier, N.B.,Choquet, D.,Imperiali, B.; Caged mono- and divalent ligands for light-assisted disruption of PDZ domain-mediated interactions.; J.Am.Chem.Soc., 135:4580-4583, 2013; PubMed: 23480637; DOI: 10.1021/ja309870q

実験手法

X-RAY DIFFRACTION (1.5 Å)