3JW3
Crystal structure of Bacillus anthracis (F96I) dihydrofolate reductase complexed with NADPH and Trimethoprim
Summary for 3JW3
Entry DOI | 10.2210/pdb3jw3/pdb |
Related | 3EOB 3JV5 3JVX |
Descriptor | Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM, ... (4 entities in total) |
Functional Keywords | oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Bacillus anthracis |
Total number of polymer chains | 2 |
Total formula weight | 42046.99 |
Authors | Anderson, A.C.,Beierlein, J.M.,Karri, N.G. (deposition date: 2009-09-17, release date: 2010-09-15, Last modification date: 2023-09-06) |
Primary citation | Beierlein, J.M.,Karri, N.G.,Anderson, A.C. Mutational Studies into Trimethoprim Resistance in Bacillus anthracis Dihydrofolate Reductase To be Published, |
Experimental method | X-RAY DIFFRACTION (2.57 Å) |
Structure validation
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