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3JW3

Crystal structure of Bacillus anthracis (F96I) dihydrofolate reductase complexed with NADPH and Trimethoprim

Summary for 3JW3
Entry DOI10.2210/pdb3jw3/pdb
Related3EOB 3JV5 3JVX
DescriptorDihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, TRIMETHOPRIM, ... (4 entities in total)
Functional Keywordsoxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological sourceBacillus anthracis
Total number of polymer chains2
Total formula weight42046.99
Authors
Anderson, A.C.,Beierlein, J.M.,Karri, N.G. (deposition date: 2009-09-17, release date: 2010-09-15, Last modification date: 2023-09-06)
Primary citationBeierlein, J.M.,Karri, N.G.,Anderson, A.C.
Mutational Studies into Trimethoprim Resistance in Bacillus anthracis Dihydrofolate Reductase
To be Published,
Experimental method
X-RAY DIFFRACTION (2.57 Å)
Structure validation

226707

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