3JV7

Structure of ADH-A from Rhodococcus ruber

3JV7 の概要

• エントリーDOI: 10.2210/pdb3jv7/pdb
• 分子名称: ADH-A, ZINC ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... (6 entities in total)
• 機能のキーワード: dehydrogenase, nucleotide binding, rossmann-fold, oxidoreductase
• 由来する生物種: Rhodococcus ruber
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 144774.33

構造登録者

Karabec, M.,Lyskowski, A.,Gruber, K. (登録日: 2009-09-16, 公開日: 2010-08-25, 最終更新日: 2023-11-01)

主引用文献

Karabec, M.,Lyskowski, A.,Tauber, K.C.,Steinkellner, G.,Kroutil, W.,Grogan, G.,Gruber, K.
Structural insights into substrate specificity and solvent tolerance in alcohol dehydrogenase ADH-'A' from Rhodococcus ruber DSM 44541.
Chem.Commun.(Camb.), 2010

PubMed Abstract: The structure of the alcohol dehydrogenase ADH-'A' from Rhodococcus ruber reveals possible reasons for its remarkable tolerance to organic co-solvents and suggests new directions for structure-informed mutagenesis to produce enzymes of altered substrate specificity or improved selectivity.

PubMed: 20676439
DOI: 10.1039/c0cc00929f

実験手法

X-RAY DIFFRACTION (2 Å)