3JUQ

Crystal Structure of PhzA/B from Burkholderia cepacia R18194 cocrystallized with 2 mM racemic 5-bromo-2-(piperidin-3-ylamino)benzoic acid

Summary for 3JUQ

• Entry DOI: 10.2210/pdb3juq/pdb
• Related: 3JUM 3JUN 3JUO 3JUP
• Descriptor: Phenazine biosynthesis protein A/B, 5-bromo-2-[(3R)-piperidin-3-ylamino]benzoic acid, 5-bromo-2-[(3S)-piperidin-3-ylamino]benzoate, ... (4 entities in total)
• Functional Keywords: chirality, drug design, phenazine biosynthesis, racemate, racemic mixture, biosynthetic protein
• Biological source: Burkholderia sp. (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
• Total number of polymer chains: 2
• Total formula weight: 44256.69

Authors

Mentel, M.,Breinbauer, R.,Blankenfeldt, W. (deposition date: 2009-09-15, release date: 2009-09-29, Last modification date: 2024-02-21)

• Primary citation: Mentel, M.,Blankenfeldt, W.,Breinbauer, R.; The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously; Angew.Chem.Int.Ed.Engl., 48:9084-9087, 2009; PubMed: 19876985; DOI: 10.1002/anie.200902997

Experimental method

X-RAY DIFFRACTION (1.75 Å)