3JUQ
Crystal Structure of PhzA/B from Burkholderia cepacia R18194 cocrystallized with 2 mM racemic 5-bromo-2-(piperidin-3-ylamino)benzoic acid
Summary for 3JUQ
Entry DOI | 10.2210/pdb3juq/pdb |
Related | 3JUM 3JUN 3JUO 3JUP |
Descriptor | Phenazine biosynthesis protein A/B, 5-bromo-2-[(3R)-piperidin-3-ylamino]benzoic acid, 5-bromo-2-[(3S)-piperidin-3-ylamino]benzoate, ... (4 entities in total) |
Functional Keywords | chirality, drug design, phenazine biosynthesis, racemate, racemic mixture, biosynthetic protein |
Biological source | Burkholderia sp. (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) |
Total number of polymer chains | 2 |
Total formula weight | 44256.69 |
Authors | Mentel, M.,Breinbauer, R.,Blankenfeldt, W. (deposition date: 2009-09-15, release date: 2009-09-29, Last modification date: 2024-02-21) |
Primary citation | Mentel, M.,Blankenfeldt, W.,Breinbauer, R. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously Angew.Chem.Int.Ed.Engl., 48:9084-9087, 2009 Cited by PubMed: 19876985DOI: 10.1002/anie.200902997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
Download full validation report