3JUP

Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with (S)-5-bromo-2-(piperidin-3-ylamino)benzoic acid

Summary for 3JUP

Entry DOI	10.2210/pdb3jup/pdb
Related	3B4P 3BO4 3CNM 3DZL 3EX9 3JUM 3JUN 3JUO 3JUQ
Descriptor	Phenazine biosynthesis protein A/B, 5-bromo-2-[(3S)-piperidin-3-ylamino]benzoate (3 entities in total)
Functional Keywords	chirality, drug design, phenazine biosynthesis, medicinal chemistry, inhibitor, biosynthetic protein
Biological source	Burkholderia sp. (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194))
Total number of polymer chains	2
Total formula weight	43658.36
Authors	Mentel, M.,Jain, I.H.,Breinbauer, R.,Blankenfeldt, W. (deposition date: 2009-09-15, release date: 2009-09-29, Last modification date: 2024-02-21)
Primary citation	Mentel, M.,Blankenfeldt, W.,Breinbauer, R. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously Angew.Chem.Int.Ed.Engl., 48:9084-9087, 2009 Cited by PubMed: 19876985 DOI: 10.1002/anie.200902997 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation