3JUO
Crystal Structure of PhzA/B from Burkholderia cepacia R18194 in complex with (R)-5-bromo-2-(piperidin-3-ylamino)benzoic acid
Summary for 3JUO
Entry DOI | 10.2210/pdb3juo/pdb |
Related | 3B4P 3BO4 3CNM 3DZL 3EX9 3JUM 3JUN 3JUP 3JUQ |
Descriptor | Phenazine biosynthesis protein A/B, 5-bromo-2-[(3R)-piperidin-3-ylamino]benzoic acid (3 entities in total) |
Functional Keywords | chirality, drug design, phenazine biosynthesis, medicinal chemistry, inhibitor, biosynthetic protein |
Biological source | Burkholderia sp. (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) |
Total number of polymer chains | 2 |
Total formula weight | 43660.38 |
Authors | Mentel, M.,Jain, I.H.,Breinbauer, R.,Blankenfeldt, W. (deposition date: 2009-09-15, release date: 2009-09-29, Last modification date: 2024-02-21) |
Primary citation | Mentel, M.,Blankenfeldt, W.,Breinbauer, R. The Active Site of an Enzyme Can Host Both Enantiomers of a Racemic Ligand Simultaneously Angew.Chem.Int.Ed.Engl., 48:9084-9087, 2009 Cited by PubMed: 19876985DOI: 10.1002/anie.200902997 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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