3JD7

The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs

3JD7 の概要

• エントリーDOI: 10.2210/pdb3jd7/pdb
• EMDBエントリー: 6636 6637 6638
• 分子名称: Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (5 entities in total)
• 機能のキーワード: picornavirus, entry intermediate, virus
• 由来する生物種: Coxsackievirus B3; 詳細
• 細胞内の位置: Capsid protein VP0: Virion . Capsid protein VP4: Virion . Capsid protein VP2: Virion . Capsid protein VP3: Virion . Capsid protein VP1: Virion . Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3AB: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Viral protein genome-linked: Virion . Protease 3C: Host cytoplasm . Protein 3CD: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . RNA-directed RNA polymerase: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : Q66282 Q66282 Q66282 Q66282
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 94091.83

構造登録者

Lee, H.,Shingler, K.L.,Organtini, L.J.,Ashley, R.E.,Makhov, A.M.,Conway, J.F.,Hafenstein, S. (登録日: 2016-04-29, 公開日: 2016-09-14, 最終更新日: 2024-02-21)

• 主引用文献: Lee, H.,Shingler, K.L.,Organtini, L.J.,Ashley, R.E.,Makhov, A.M.,Conway, J.F.,Hafenstein, S.; The novel asymmetric entry intermediate of a picornavirus captured with nanodiscs.; Sci Adv, 2:e1501929-e1501929, 2016; PubMed: 27574701; DOI: 10.1126/sciadv.1501929

実験手法

ELECTRON MICROSCOPY (3.9 Å)