Structure of Dark apoptosome from Drosophila melanogaster

This is a large structure.

Summary for 3J9L

EMDB informationEMD-2871 EMD-2870
DescriptorApaf-1 related killer DARK, 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE (2 entities in total)
Functional Keywordsprogrammed cell death, apoptosis
Biological sourceDrosophila melanogaster (Fruit fly)
Total number of polymer chains16
Total molecular weight1812715.99
Pang, Y.,Bai, X.,Yan, C.,Hao, Q.,Chen, Z.,Wang, J.,Scheres, S.H.W.,Shi, Y. (deposition date: 2015-02-04, release date: 2015-02-25)
Primary citation
Pang, Y.,Bai, X.C.,Yan, C.,Hao, Q.,Chen, Z.,Wang, J.W.,Scheres, S.H.,Shi, Y.
Structure of the apoptosome: mechanistic insights into activation of an initiator caspase from Drosophila.
Genes Dev., 29:277-287, 2015
PubMed: 25644603 (PDB entries with the same primary citation)
DOI: 10.1101/gad.255877.114
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers810.9%26.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j9l
no rotation
Molmil generated image of 3j9l
rotated about x axis by 90°
Molmil generated image of 3j9l
rotated about y axis by 90°
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