CryoEM structure of 40S-eIF1-eIF1A preinitiation complex

Summary for 3J80

EMDB information2764
Descriptor18S rRNA, uS2, eS1, ... (39 entities in total)
Functional Keywordssmall ribosome subunit, eukaryotic translation initiation, ribosome
Biological sourceSaccharomyces cerevisiae (yeast)
Total number of polymer chains37
Total molecular weight1208132.06
Hussain, T.,Llacer, J.L.,Fernandez, I.S.,Savva, C.G.,Ramakrishnan, V. (deposition date: 2014-08-28, release date: 2014-11-05, Last modification date: 2018-07-18)
Primary citation
Hussain, T.,Llacer, J.L.,Fernandez, I.S.,Munoz, A.,Martin-Marcos, P.,Savva, C.G.,Lorsch, J.R.,Hinnebusch, A.G.,Ramakrishnan, V.
Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell(Cambridge,Mass.), 159:597-607, 2014
PubMed: 25417110 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2014.10.001
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone94.6%12.4%0.30MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j80
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Molmil generated image of 3j80
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Molmil generated image of 3j80
rotated about y axis by 90°