3J46

Structure of the SecY protein translocation channel in action

Summary for 3J46

Related2I2P 3J01 3I8G 3J45
EMDB information5693
DescriptorProtein translocase subunit SecY, Preprotein translocase subunit SecE, Protein-export membrane protein SecG, ... (14 entities in total)
Functional Keywords70s, preprotein translocase, secyeg, protein translocation channel, nascent chain, ribosome-protein transport complex, ribosome/protein transport
Biological sourceEscherichia coli
Total number of polymer chains14
Total molecular weight256082.55
Authors
Akey, C.W.,Park, E.,Menetret, J.F.,Gumbart, J.C.,Ludtke, S.J.,Li, W.,Whynot, A.,Rapoport, T.A. (deposition date: 2013-06-18, release date: 2013-10-23, Last modification date: 2018-07-18)
Primary citation
Park, E.,Menetret, J.F.,Gumbart, J.C.,Ludtke, S.J.,Li, W.,Whynot, A.,Rapoport, T.A.,Akey, C.W.
Structure of the SecY channel during initiation of protein translocation.
Nature, 506:102-106, 2013
PubMed: 24153188 (PDB entries with the same primary citation)
DOI: 10.1038/nature12720
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone207.2%7.2%0.40MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j46
no rotation
Molmil generated image of 3j46
rotated about x axis by 90°
Molmil generated image of 3j46
rotated about y axis by 90°