3IWO
X-ray crystal structure of the extended-spectrum AmpC Y221G mutant beta-lactamase at 1.90 Angstrom resolution
Summary for 3IWO
Entry DOI | 10.2210/pdb3iwo/pdb |
Related | 3IWI 3IWQ 3IXB 3IXD 3IXG 3IXH |
Related PRD ID | PRD_900003 |
Descriptor | Beta-lactamase, beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | serine hydrolase, beta-lactamase, cephalosporinase, extended-spectrum antibiotic resistance, antibiotic resistance, hydrolase, periplasm |
Biological source | Escherichia coli |
Cellular location | Periplasm: P00811 |
Total number of polymer chains | 2 |
Total formula weight | 80085.46 |
Authors | Shoichet, B.K.,Thomas, V.L. (deposition date: 2009-09-03, release date: 2010-02-16, Last modification date: 2023-09-06) |
Primary citation | Thomas, V.L.,McReynolds, A.C.,Shoichet, B.K. Structural bases for stability-function tradeoffs in antibiotic resistance. J.Mol.Biol., 396:47-59, 2010 Cited by PubMed: 19913034DOI: 10.1016/j.jmb.2009.11.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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