3IU2
Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096
Summary for 3IU2
Entry DOI | 10.2210/pdb3iu2/pdb |
Related | 1rxt 3IU1 |
Descriptor | Glycylpeptide N-tetradecanoyltransferase 1, TETRADECANOYL-COA, (2R)-2-{4-hydroxy-5-methoxy-2-[3-(4-methylpiperazin-1-yl)propyl]phenyl}-3-pyridin-3-yl-1,3-thiazolidin-4-one, ... (4 entities in total) |
Functional Keywords | transferase, n-myristoyltransferase, nmt1, acyltransferas, acyltransferase, phosphoprotein, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P30419 |
Total number of polymer chains | 2 |
Total formula weight | 91923.59 |
Authors | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R.,Structural Genomics Consortium (SGC) (deposition date: 2009-08-29, release date: 2009-09-15, Last modification date: 2024-02-21) |
Primary citation | Qiu, W.,Hutchinson, A.,Wernimont, A.,Lin, Y.-H.,Kania, A.,Ravichandran, M.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Wyatt, P.G.,Ferguson, M.A.J.,Frearson, J.A.,Brand, S.Y.,Robinson, D.A.,Bochkarev, A.,Hui, R. Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA and inhibitor DDD90096 To be Published, |
Experimental method |
Structure validation
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