3ISD

Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch

3ISD の概要

• エントリーDOI: 10.2210/pdb3isd/pdb
• 関連するPDBエントリー: 1BPX 3C2M 3ISB 3ISC
• 分子名称: DNA polymerase beta, 5'-D(P*GP*TP*CP*GP*G)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ... (9 entities in total)
• 機能のキーワード: nucleotidyl transferase, dna polymerase beta, abasic site, tetrahydrofuran, ternary complex, gapped dna, 'a-rule', dna damage, dna repair, dna replication, dna synthesis, dna-binding, dna-directed dna polymerase, lyase, magnesium, metal-binding, methylation, nucleotidyltransferase, nucleus, polymorphism, sodium, transferase, transferase-dna complex, transferase/dna
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 48618.51

構造登録者

Beard, W.A.,Shock, D.D.,Batra, V.K.,Pedersen, L.C.,Wilson, S.H. (登録日: 2009-08-25, 公開日: 2009-09-15, 最終更新日: 2023-09-06)

• 主引用文献: Beard, W.A.,Shock, D.D.,Batra, V.K.,Pedersen, L.C.,Wilson, S.H.; DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".; J.Biol.Chem., 284:31680-31689, 2009; PubMed: 19759017; DOI: 10.1074/jbc.M109.029843

実験手法

X-RAY DIFFRACTION (2.6 Å)