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3ISD

Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
DNA polymerase betapolymer33538241.71UniProt (P06746)
Pfam (PF14716)
Pfam (PF10391)
Pfam (PF14792)
Pfam (PF14791)
Homo sapiens (Human)
2B
(D)
5'-D(P*GP*TP*CP*GP*G)-3'polymer51536.01synthetic construct
3C
(P)
5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3'polymer103061.01synthetic construct
4D
(T)
5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'polymer164720.01synthetic construct
5E, F, P
(A, P)
SODIUM IONnon-polymer23.03Chemie (NA)
6G, H, I, J, K...
(A, T)
MANGANESE (II) IONnon-polymer54.98Chemie (MN)
7N
(A)
2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosinenon-polymer489.21Chemie (F2A)
8O
(A)
1,2-ETHANEDIOLnon-polymer62.11Chemie (EDO)
9R, S, T, U
(A, D, P, T)
waterwater18.0268Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight47558.8
Non-Polymers*Number of molecules13
Total formula weight1059.8
All*Total formula weight48618.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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