3IQF

Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methenyl-tetrahydromethanopterin

3IQF の概要

• エントリーDOI: 10.2210/pdb3iqf/pdb
• 関連するPDBエントリー: 3IQE 3IQZ
• 分子名称: F420-dependent methylenetetrahydromethanopterin dehydrogenase, 1-{4-[(6S,6aR,7R)-3-amino-6,7-dimethyl-1-oxo-1,2,5,6,6a,7-hexahydro-8H-imidazo[1,5-f]pteridin-10-ium-8-yl]phenyl}-1-deoxy-5-O-{5-O-[(S)-{[(1S)-1,3-dicarboxypropyl]oxy}(hydroxy)phosphoryl]-alpha-D-ribofuranosyl}-D-ribitol, CALCIUM ION, ... (5 entities in total)
• 機能のキーワード: binary complex of protein and substrate, methanogenesis, one-carbon metabolism, oxidoreductase
• 由来する生物種: Methanopyrus kandleri
• タンパク質・核酸の鎖数: 12
• 化学式量合計: 386746.38

構造登録者

Ceh, K.E.,Demmer, U.,Warkentin, E.,Moll, J.,Thauer, R.K.,Shima, S.,Ermler, U. (登録日: 2009-08-20, 公開日: 2009-10-06, 最終更新日: 2023-11-01)

• 主引用文献: Ceh, K.,Demmer, U.,Warkentin, E.,Moll, J.,Thauer, R.K.,Shima, S.,Ermler, U.; Structural basis of the hydride transfer mechanism in F(420)-dependent methylenetetrahydromethanopterin dehydrogenase; Biochemistry, 48:10098-10105, 2009; PubMed: 19761261; DOI: 10.1021/bi901104d

実験手法

X-RAY DIFFRACTION (2.1 Å)