3IQ3

Crystal Structure of Bothropstoxin-I complexed with polietilene glicol 4000 - crystallized at 283 K

3IQ3 の概要

• エントリーDOI: 10.2210/pdb3iq3/pdb
• 関連するPDBエントリー: 2OK9 2OQD 2QOG 3HZD 3I3H 3I3I
• 分子名称: Phospholipase A2 homolog bothropstoxin-1, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: homologue phospholipase a2, bothropstoxin-i, bthtx-i_10c, lys49-pla2 from bothrops jararacussu, snake venom, antibiotic, antimicrobial, disulfide bond, myotoxin, secreted, toxin
• 由来する生物種: Bothrops jararacussu (Jararacussu)
• 細胞内の位置: Secreted: Q90249
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28759.73

構造登録者

Salvador, G.H.M.,Marchi-Salvador, D.P.,Silva, M.C.O.,Soares, A.M.,Fontes, M.R.M. (登録日: 2009-08-19, 公開日: 2009-10-27, 最終更新日: 2023-09-06)

• 主引用文献: Fernandes, C.A.,Marchi-Salvador, D.P.,Salvador, G.M.,Silva, M.C.,Costa, T.R.,Soares, A.M.,Fontes, M.R.; Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s.; J.Struct.Biol., 171:31-43, 2010; PubMed: 20371382; DOI: 10.1016/j.jsb.2010.03.019

実験手法

X-RAY DIFFRACTION (1.55 Å)