3IOL

Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor

Summary for 3IOL

Entry DOI	10.2210/pdb3iol/pdb
Related	3C59 3C5T
Descriptor	Glucagon-like peptide 1 receptor, Glucagon, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside, ... (4 entities in total)
Functional Keywords	receptor-ligand complex, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, membrane, receptor, transducer, transmembrane, amidation, cleavage on pair of basic residues, hormone, secreted, signaling protein-signaling protein complex, signaling protein/signaling protein
Biological source	Homo sapiens (human) More
Cellular location	Cell membrane ; Multi- pass membrane protein : P43220 Secreted: P01275
Total number of polymer chains	2
Total formula weight	18597.64
Authors	Reedtz-Runge, S. (deposition date: 2009-08-14, release date: 2009-10-27, Last modification date: 2023-11-01)
Primary citation	Underwood, C.R.,Garibay, P.,Knudsen, L.B.,Hastrup, S.,Peters, G.H.,Rudolph, R.,Reedtz-Runge, S. Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor J.Biol.Chem., 285:723-730, 2010 Cited by PubMed: 19861722 DOI: 10.1074/jbc.M109.033829 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation