3IOL
Crystal structure of Glucagon-Like Peptide-1 in complex with the extracellular domain of the Glucagon-Like Peptide-1 Receptor
3IOL の概要
エントリーDOI | 10.2210/pdb3iol/pdb |
関連するPDBエントリー | 3C59 3C5T |
分子名称 | Glucagon-like peptide 1 receptor, Glucagon, decyl 4-O-alpha-D-glucopyranosyl-1-thio-beta-D-glucopyranoside, ... (4 entities in total) |
機能のキーワード | receptor-ligand complex, cell membrane, disulfide bond, g-protein coupled receptor, glycoprotein, membrane, receptor, transducer, transmembrane, amidation, cleavage on pair of basic residues, hormone, secreted, signaling protein-signaling protein complex, signaling protein/signaling protein |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Cell membrane ; Multi- pass membrane protein : P43220 Secreted: P01275 |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 18597.64 |
構造登録者 | |
主引用文献 | Underwood, C.R.,Garibay, P.,Knudsen, L.B.,Hastrup, S.,Peters, G.H.,Rudolph, R.,Reedtz-Runge, S. Crystal structure of glucagon-like peptide-1 in complex with the extracellular domain of the glucagon-like peptide-1 receptor J.Biol.Chem., 285:723-730, 2010 Cited by PubMed: 19861722DOI: 10.1074/jbc.M109.033829 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.1 Å) |
構造検証レポート
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