3IL6
Structure of E. faecalis FabH in complex with 2-({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxybenzoyl}amino)benzoic acid
Summary for 3IL6
Entry DOI | 10.2210/pdb3il6/pdb |
Related | 3IL3 3IL4 3IL5 3IL7 3IL9 |
Descriptor | 3-oxoacyl-[acyl-carrier-protein] synthase 3, 2-[({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxyphenyl}carbonyl)amino]benzoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | fabh, fatty acid biosynthesis, antibiotic, acyltransferase, cytoplasm, lipid synthesis, multifunctional enzyme, transferase |
Biological source | Enterococcus faecalis |
Cellular location | Cytoplasm (Probable): Q820T1 |
Total number of polymer chains | 1 |
Total formula weight | 36206.77 |
Authors | Gajiwala, K.S.,Margosiak, S.,Lu, J.,Cortez, J.,Su, Y.,Nie, Z.,Appelt, K. (deposition date: 2009-08-06, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Gajiwala, K.S.,Margosiak, S.,Lu, J.,Cortez, J.,Su, Y.,Nie, Z.,Appelt, K. Crystal structures of bacterial FabH suggest a molecular basis for the substrate specificity of the enzyme. Febs Lett., 583:2939-2946, 2009 Cited by PubMed: 19665020DOI: 10.1016/j.febslet.2009.08.001 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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