3IL6
Structure of E. faecalis FabH in complex with 2-({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxybenzoyl}amino)benzoic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | polymer | 321 | 35185.9 | 1 | UniProt (Q820T1) Pfam (PF08545) Pfam (PF08541) | Enterococcus faecalis | 3-oxoacyl-[acyl-carrier-protein] synthase III, Beta-ketoacyl-ACP synthase III, KAS III |
| 2 | B (A) | 2-[({4-[(3R,5S)-3,5-dimethylpiperidin-1-yl]-3-phenoxyphenyl}carbonyl)amino]benzoic acid | non-polymer | 444.5 | 1 | Chemie (B83) | |||
| 3 | C, D, E, F, G... (A) | SULFATE ION | non-polymer | 96.1 | 6 | Chemie (SO4) | |||
| 4 | I (A) | water | water | 18.0 | 112 | Chemie (HOH) |
Sequence modifications
A: 5 - 325 (UniProt: Q820T1)
| PDB | External Database | Details |
|---|---|---|
| Ala 36 | Asp 32 | engineered mutation |
| Ala 37 | Glu 33 | engineered mutation |
| Thr 192 | Ala 188 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 35185.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1020.9 | |
| All* | Total formula weight | 36206.8 |
