3IKO

Crystal structure of the heterotrimeric Sec13-Nup145C-Nup84 nucleoporin complex

Summary for 3IKO

Entry DOI	10.2210/pdb3iko/pdb
Descriptor	Protein transport protein SEC13, Nucleoporin NUP145C, Nucleoporin NUP84 (3 entities in total)
Functional Keywords	npc, transport, wd repeat, autocatalytic cleavage, mrna transport, nuclear pore complex, nucleus, phosphoprotein, translocation, protein transport, coiled coil, membrane, hydrolase, rna-binding, cytoplasmic vesicle, endoplasmic reticulum, er-golgi transport, nuclear protein, structural protein
Biological source	Saccharomyces cerevisiae (yeast) More
Cellular location	Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side: Q04491 Nucleoporin NUP145C: Nucleus, nuclear pore complex. Nucleoporin NUP145N: Nucleus, nuclear pore complex: P49687 Nucleus, nuclear pore complex: P52891
Total number of polymer chains	9
Total formula weight	410884.97
Authors	Nagy, V.,Hsia, K.-C.,Debler, E.W.,Davenport, A.,Blobel, G.,Hoelz, A. (deposition date: 2009-08-06, release date: 2009-10-13, Last modification date: 2024-02-21)
Primary citation	Nagy, V.,Hsia, K.C.,Debler, E.W.,Kampmann, M.,Davenport, A.M.,Blobel, G.,Hoelz, A. Structure of a trimeric nucleoporin complex reveals alternate oligomerization states. Proc.Natl.Acad.Sci.USA, 106:17693-17698, 2009 Cited by PubMed: 19805193 DOI: 10.1073/pnas.0909373106 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation