3IK7
Human glutathione transferase a4-4 with GSDHN
Summary for 3IK7
Entry DOI | 10.2210/pdb3ik7/pdb |
Related | 3IK9 |
Descriptor | Glutathione S-transferase A4, (S)-2-amino-5-((R)-1-(carboxymethylamino)-3-((3S,4R)-1,4-dihydroxynonan-3-ylthio)-1-oxopropan-2-ylamino)-5-oxopentanoic acid, SULFATE ION, ... (4 entities in total) |
Functional Keywords | human gst a4-4, enzyme, transferase, cytoplasm, polymorphism |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: O15217 |
Total number of polymer chains | 4 |
Total formula weight | 104910.69 |
Authors | Balogh, L.M.,Le Trong, I.,Atkins, W.M.,Stenkamp, R.E. (deposition date: 2009-08-05, release date: 2010-06-23, Last modification date: 2023-09-06) |
Primary citation | Balogh, L.M.,Le Trong, I.,Kripps, K.A.,Shireman, L.M.,Stenkamp, R.E.,Zhang, W.,Mannervik, B.,Atkins, W.M. Substrate specificity combined with stereopromiscuity in glutathione transferase A4-4-dependent metabolism of 4-hydroxynonenal. Biochemistry, 49:1541-1548, 2010 Cited by PubMed: 20085333DOI: 10.1021/bi902038u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.97 Å) |
Structure validation
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