3IIY

Crystal structure of Eed in complex with a trimethylated histone H1K26 peptide

Summary for 3IIY

• Entry DOI: 10.2210/pdb3iiy/pdb
• Related: 2QXV 3IIW 3IJ0 3IJ1 3IJC
• Descriptor: Polycomb protein EED, Histone H1K26 peptide (3 entities in total)
• Functional Keywords: wd40 domain, alternative initiation, alternative splicing, chromatin regulator, nucleus, phosphoprotein, repressor, transcription, transcription regulation, wd repeat, gene regulation
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: O75530
• Total number of polymer chains: 2
• Total formula weight: 43302.37

Authors

Justin, N.,Sharpe, M.L.,Martin, S.,Taylor, W.R.,De Marco, V.,Gamblin, S.J. (deposition date: 2009-08-03, release date: 2009-09-15, Last modification date: 2024-04-03)

• Primary citation: Margueron, R.,Justin, N.,Ohno, K.,Sharpe, M.L.,Son, J.,Drury, W.J.,Voigt, P.,Martin, S.R.,Taylor, W.R.,De Marco, V.,Pirrotta, V.,Reinberg, D.,Gamblin, S.J.; Role of the polycomb protein EED in the propagation of repressive histone marks.; Nature, 461:762-767, 2009; PubMed: 19767730; DOI: 10.1038/nature08398

Experimental method

X-RAY DIFFRACTION (2.65 Å)