3IGC

Smallpox virus topoisomerase-DNA transition state

Summary for 3IGC

• Entry DOI: 10.2210/pdb3igc/pdb
• Descriptor: DNA topoisomerase 1, 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', 5'-D(*AP*TP*TP*CP*C)-3', ... (6 entities in total)
• Functional Keywords: topoisomerase, protein-dna complex, poxvirus, isomerase, atp-binding, dna-binding, late protein, nucleotide-binding, isomerase-dna complex, isomerase/dna
• Biological source: Variola virus (smallpox virus); More
• Total number of polymer chains: 4
• Total formula weight: 46484.80

Authors

Perry, K.,Hwang, Y.,Bushman, F.D.,Van Duyne, G.D. (deposition date: 2009-07-27, release date: 2010-03-02, Last modification date: 2023-09-06)

• Primary citation: Perry, K.,Hwang, Y.,Bushman, F.D.,Van Duyne, G.D.; Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic.; Structure, 18:127-137, 2010; PubMed: 20152159; DOI: 10.1016/j.str.2009.10.020

Experimental method

X-RAY DIFFRACTION (2.1 Å)