3IEW

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei with bound CTP and CDP

Summary for 3IEW

Entry DOI	10.2210/pdb3iew/pdb
Related	3E0D 3E0E 3F0F 3F0G 3IEQ
Descriptor	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION, CYTIDINE-5'-DIPHOSPHATE, ... (6 entities in total)
Functional Keywords	ispf, structural genomics, isoprene biosynthesis, lyase, metal-binding, seattle structural genomics center for infectious disease, ssgcid
Biological source	Burkholderia pseudomallei
Total number of polymer chains	3
Total formula weight	60039.16
Authors	Staker, B.L.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (deposition date: 2009-07-23, release date: 2009-08-18, Last modification date: 2023-09-06)
Primary citation	Begley, D.W.,Hartley, R.C.,Davies, D.R.,Edwards, T.E.,Leonard, J.T.,Abendroth, J.,Burris, C.A.,Bhandari, J.,Myler, P.J.,Staker, B.L.,Stewart, L.J. Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12:63-76, 2011 Cited by PubMed: 21359640 DOI: 10.1007/s10969-011-9102-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation