3IDC

Crystal structure of (102-265)RIIb:C holoenzyme of cAMP-dependent protein kinase

3IDC の概要

• エントリーDOI: 10.2210/pdb3idc/pdb
• 関連するPDBエントリー: 1CX4 1RGS 2QCS 2QVS 3IDB
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase type II-beta regulatory subunit, MANGANESE (II) ION, ... (5 entities in total)
• 機能のキーワード: pka, camp, spr, affinity, kinase, linker, rii holoenzyme, alternative splicing, atp-binding, cytoplasm, lipoprotein, myristate, nucleotide-binding, nucleus, phosphoprotein, serine/threonine-protein kinase, transferase, acetylation, camp-binding
• 由来する生物種: Mus musculus (mouse); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60012.47

構造登録者

Brown, S.H.J.,Wu, J.,Kim, C.,Alberto, K.,Taylor, S.S. (登録日: 2009-07-20, 公開日: 2009-09-29, 最終更新日: 2023-09-06)

• 主引用文献: Brown, S.H.,Wu, J.,Kim, C.,Alberto, K.,Taylor, S.S.; Novel isoform-specific interfaces revealed by PKA RIIbeta holoenzyme structures.; J.Mol.Biol., 393:1070-1082, 2009; PubMed: 19748511; DOI: 10.1016/j.jmb.2009.09.014

実験手法

X-RAY DIFFRACTION (2.7 Å)