3IA3

A cis-proline in alpha-hemoglobin stabilizing Protein directs the structural reorganization of alpha-hemoglobin

3IA3 の概要

• エントリーDOI: 10.2210/pdb3ia3/pdb
• 分子名称: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
• 機能のキーワード: hemoglobin, cis-proline, ahsp, stabilization, chaperone, cytoplasm, polymorphism, acetylation, disease mutation, glycation, glycoprotein, heme, iron, metal-binding, oxygen transport, phosphoprotein, transport
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: Q9NZD4
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 53728.84

構造登録者

Feng, L.,Jeffrey, P.D.,Shi, Y. (登録日: 2009-07-13, 公開日: 2009-07-28, 最終更新日: 2024-02-21)

• 主引用文献: Gell, D.A.,Feng, L.,Zhou, S.,Jeffrey, P.D.,Bendak, K.,Gow, A.,Weiss, M.J.,Shi, Y.,Mackay, J.P.; A cis-proline in alpha-hemoglobin stabilizing protein directs the structural reorganization of alpha-hemoglobin.; J.Biol.Chem., 284:29462-29469, 2009; PubMed: 19706593; DOI: 10.1074/jbc.M109.027045

実験手法

X-RAY DIFFRACTION (3.2 Å)