3I9G

Crystal structure of the LT1009 (SONEPCIZUMAB) antibody Fab fragment in complex with sphingosine-1-phosphate

3I9G の概要

• エントリーDOI: 10.2210/pdb3i9g/pdb
• 分子名称: Sonepcizumab antibody Fab fragment, heavy chain, Sonepcizumab antibody Fab fragment, light chain, CALCIUM ION, ... (6 entities in total)
• 機能のキーワード: antibody, fab, sphingosine-1-phosphate, calcium, immunoglobin, igg, immune system
• 由来する生物種: Mus musculus; 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 48051.25

構造登録者

Huxford, T. (登録日: 2009-07-10, 公開日: 2009-09-29, 最終更新日: 2011-07-13)

• 主引用文献: Wojciak, J.M.,Zhu, N.,Schuerenberg, K.T.,Moreno, K.,Shestowsky, W.S.,Hiraiwa, M.,Sabbadini, R.,Huxford, T.; The crystal structure of sphingosine-1-phosphate in complex with a Fab fragment reveals metal bridging of an antibody and its antigen.; Proc.Natl.Acad.Sci.USA, 106:17717-17722, 2009; PubMed: 19815502; DOI: 10.1073/pnas.0906153106

実験手法

X-RAY DIFFRACTION (1.9 Å)