3I8V

Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone

3I8V の概要

• エントリーDOI: 10.2210/pdb3i8v/pdb
• 分子名称: cAMP-specific 3',5'-cyclic phosphodiesterase 4A, ZINC ION, MAGNESIUM ION, ... (7 entities in total)
• 機能のキーワード: cyclic-amp specific, camp, hydrolase, membrane, phosphoprotein
• 由来する生物種: Homo sapiens (human)
• 細胞内の位置: Isoform 1: Cytoplasm, perinuclear region. Isoform 2: Cytoplasm, perinuclear region. Isoform 4: Membrane; Peripheral membrane protein. Isoform 6: Cytoplasm, perinuclear region. Isoform 7: Cytoplasm: P27815
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 82449.81

構造登録者

Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M. (登録日: 2009-07-10, 公開日: 2009-07-21, 最終更新日: 2023-11-22)

• 主引用文献: Cheng, R.K.Y.,Crawley, L.,Barker, J.,Wood, M.,Felicetti, B.,Whittaker, M.; Crystal structure of human PDE4a with 4-(3-butoxy-4-methoxyphenyl)methyl-2-imidazolidone; To be Published,

実験手法

X-RAY DIFFRACTION (2.25 Å)