3I3J
Crystal Structure of the Bromodomain of Human EP300
3I3J の概要
エントリーDOI | 10.2210/pdb3i3j/pdb |
分子名称 | Histone acetyltransferase p300, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... (5 entities in total) |
機能のキーワード | structural genomics bromodomain, p300, consortium, sgc, structural genomics consortium, bromodomain, cell cycle, citrullination, disease mutation, host-virus interaction, metal-binding, methylation, nucleus, phosphoprotein, transcription, transcription regulation, transferase, zinc-finger |
由来する生物種 | Homo sapiens (human) |
細胞内の位置 | Cytoplasm: Q09472 |
タンパク質・核酸の鎖数 | 12 |
化学式量合計 | 176332.74 |
構造登録者 | Filippakopoulos, P.,Picaud, S.,Phillips, C.,Pike, A.C.W.,Muniz, J.,Roos, A.,Chaikuad, A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Weigelt, J.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2009-06-30, 公開日: 2009-07-28, 最終更新日: 2023-11-01) |
主引用文献 | Filippakopoulos, P.,Picaud, S.,Mangos, M.,Keates, T.,Lambert, J.P.,Barsyte-Lovejoy, D.,Felletar, I.,Volkmer, R.,Muller, S.,Pawson, T.,Gingras, A.C.,Arrowsmith, C.H.,Knapp, S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149:214-231, 2012 Cited by PubMed: 22464331DOI: 10.1016/j.cell.2012.02.013 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.33 Å) |
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