3I2E
Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1)
Summary for 3I2E
Entry DOI | 10.2210/pdb3i2e/pdb |
Descriptor | N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (2 entities in total) |
Functional Keywords | ddah, hydrolase, nitric oxide synthase regulator, metal-binding, zinc |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 67246.98 |
Authors | Monzingo, A.F.,Wang, Y.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W. (deposition date: 2009-06-29, release date: 2009-08-25, Last modification date: 2023-09-06) |
Primary citation | Wang, Y.,Monzingo, A.F.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W. Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide. Biochemistry, 48:8624-8635, 2009 Cited by PubMed: 19663506DOI: 10.1021/bi9007098 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.03 Å) |
Structure validation
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