3I2E

Crystal structure of human dimethylarginine dymethylaminohydrolase-1 (DDAH-1)

3I2E の概要

• エントリーDOI: 10.2210/pdb3i2e/pdb
• 分子名称: N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (2 entities in total)
• 機能のキーワード: ddah, hydrolase, nitric oxide synthase regulator, metal-binding, zinc
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 67246.98

構造登録者

Monzingo, A.F.,Wang, Y.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W. (登録日: 2009-06-29, 公開日: 2009-08-25, 最終更新日: 2023-09-06)

• 主引用文献: Wang, Y.,Monzingo, A.F.,Hu, S.,Schaller, T.H.,Robertus, J.D.,Fast, W.; Developing dual and specific inhibitors of dimethylarginine dimethylaminohydrolase-1 and nitric oxide synthase: toward a targeted polypharmacology to control nitric oxide.; Biochemistry, 48:8624-8635, 2009; PubMed: 19663506; DOI: 10.1021/bi9007098

実験手法

X-RAY DIFFRACTION (2.03 Å)