3I03

Crystal structure of bothropstoxin-I chemically modified by p-bromophenacyl bromide (BPB) - monomeric form at a high resolution

Summary for 3I03

Entry DOI	10.2210/pdb3i03/pdb
Related	1Y4L 2Q2J 3CXI 3CYL 3HZD 3HZW
Descriptor	Phospholipase A2 homolog bothropstoxin-1, p-Bromophenacyl bromide, ISOPROPYL ALCOHOL, ... (4 entities in total)
Functional Keywords	lys49-pla2s, phospholipase homologue, bothropstoxin-i, p-bromophenacyl bromide, myotoxicity, antibiotic, antimicrobial, disulfide bond, myotoxin, secreted, toxin
Biological source	Bothrops jararacussu (snake)
Total number of polymer chains	1
Total formula weight	14091.17
Authors	Marchi-Salvador, D.P.,Fernandes, C.A.H.,Soares, A.M.,Fontes, M.R.M. (deposition date: 2009-06-24, release date: 2010-05-12, Last modification date: 2023-09-06)
Primary citation	Fernandes, C.A.,Marchi-Salvador, D.P.,Salvador, G.M.,Silva, M.C.,Costa, T.R.,Soares, A.M.,Fontes, M.R. Comparison between apo and complexed structures of bothropstoxin-I reveals the role of Lys122 and Ca(2+)-binding loop region for the catalytically inactive Lys49-PLA(2)s. J.Struct.Biol., 171:31-43, 2010 Cited by PubMed: 20371382 DOI: 10.1016/j.jsb.2010.03.019 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.48 Å)

Structure validation