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3HZG

Crystal structure of mycobacterium tuberculosis thymidylate synthase X bound with FAD

3HZG の概要
エントリーDOI10.2210/pdb3hzg/pdb
関連するPDBエントリー3GWC
分子名称Thymidylate synthase thyX, PHOSPHATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... (5 entities in total)
機能のキーワードthyx, fad, thymidylate synthase, flavoprotein, methyltransferase, nucleotide biosynthesis, transferase, structural genomics, seattle structural genomics center for infectious disease, ssgcid
由来する生物種Mycobacterium tuberculosis
タンパク質・核酸の鎖数4
化学式量合計119070.94
構造登録者
Staker, B.L.,Rathod, P.,Hunter, J.,Seattle Structural Genomics Center for Infectious Disease (SSGCID) (登録日: 2009-06-23, 公開日: 2009-07-07, 最終更新日: 2023-09-06)
主引用文献Baugh, L.,Phan, I.,Begley, D.W.,Clifton, M.C.,Armour, B.,Dranow, D.M.,Taylor, B.M.,Muruthi, M.M.,Abendroth, J.,Fairman, J.W.,Fox, D.,Dieterich, S.H.,Staker, B.L.,Gardberg, A.S.,Choi, R.,Hewitt, S.N.,Napuli, A.J.,Myers, J.,Barrett, L.K.,Zhang, Y.,Ferrell, M.,Mundt, E.,Thompkins, K.,Tran, N.,Lyons-Abbott, S.,Abramov, A.,Sekar, A.,Serbzhinskiy, D.,Lorimer, D.,Buchko, G.W.,Stacy, R.,Stewart, L.J.,Edwards, T.E.,Van Voorhis, W.C.,Myler, P.J.
Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95:142-148, 2015
Cited by
PubMed: 25613812
DOI: 10.1016/j.tube.2014.12.003
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.45 Å)
構造検証レポート
Validation report summary of 3hzg
検証レポート(詳細版)ダウンロードをダウンロード

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件を2024-03-27に公開中

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