3HZF

Structure of TR-alfa bound to selective thyromimetic GC-1 in C2 space group

3HZF の概要

• エントリーDOI: 10.2210/pdb3hzf/pdb
• 分子名称: Thyroid hormone receptor, alpha isoform 1 variant, {4-[4-hydroxy-3-(1-methylethyl)benzyl]-3,5-dimethylphenoxy}acetic acid (3 entities in total)
• 機能のキーワード: nuclear receptor, ligand binding domain, dna-binding, metal-binding, nucleus, receptor, transcription, transcription regulation, zinc-finger
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 31334.61

構造登録者

Aparicio, R.,Bleicher, L.,Polikarpov, I. (登録日: 2009-06-23, 公開日: 2009-07-21, 最終更新日: 2023-09-06)

• 主引用文献: Bleicher, L.,Aparicio, R.,Nunes, F.M.,Martinez, L.,Gomes Dias, S.M.,Figueira, A.C.,Santos, M.A.,Venturelli, W.H.,da Silva, R.,Donate, P.M.,Neves, F.A.,Simeoni, L.A.,Baxter, J.D.,Webb, P.,Skaf, M.S.,Polikarpov, I.; Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms.; Bmc Struct.Biol., 8:8-8, 2008; PubMed: 18237438; DOI: 10.1186/1472-6807-8-8

実験手法