3HZ5

Crystal structure of Hsp90 with fragment Z064

Summary for 3HZ5

Related3HYY 3HYZ 3HZ1
DescriptorHeat shock protein HSP 90-alpha, N-[4-(5-furan-2-yl-3-methyl-1H-pyrazol-4-yl)butyl]-N-methyl-7H-purin-6-amine (3 entities in total)
Functional Keywordsnucleotide binding, atp-binding, chaperone, nucleotide-binding, phosphoprotein, stress response
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm P07900
Total number of polymer chains1
Total molecular weight28310.74
Authors
Barker, J.,Mather, O.,Cheng, R.K.Y.,Palan, S.,Felicetti, B.,Whittaker, M. (deposition date: 2009-06-23, release date: 2010-07-14, Last modification date: 2011-07-13)
Primary citation
Barker, J.,Mather, O.,Cheng, R.K.Y.,Palan, S.,Felicetti, B.,Whittaker, M.
Crystal structure of Hsp90 with fragment Z064
to be published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.240100 0.6% 4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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170172
PDB entries from 2020-10-21