3HXY

Crystal Structure of catalytic fragment of E. coli AlaRS in complex with AMPPCP, Ala-AMP and PCP

3HXY の概要

• エントリーDOI: 10.2210/pdb3hxy/pdb
• 関連するPDBエントリー: 3HXU 3HXV 3HXW 3HXX 3HXZ 3HY0 3HY1
• 分子名称: Alanyl-tRNA synthetase, 5'-O-[(R)-{[(2S)-2-aminopropanoyl]oxy}(hydroxy)phosphoryl]adenosine, METHYLENEDIPHOSPHONIC ACID, ... (8 entities in total)
• 機能のキーワード: aminoacyl-trna synthetase, ligase, protein biosynthesis, nucleotide-binding, amino acid-binding, atp-binding, metal-binding, zinc-finger
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P00957
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 51353.17

構造登録者

Guo, M.,Yang, X.-L.,Schimmel, P. (登録日: 2009-06-22, 公開日: 2009-12-15, 最終更新日: 2024-02-21)

• 主引用文献: Guo, M.,Chong, Y.E.,Shapiro, R.,Beebe, K.,Yang, X.L.,Schimmel, P.; Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma.; Nature, 462:808-812, 2009; PubMed: 20010690; DOI: 10.1038/nature08612

実験手法

X-RAY DIFFRACTION (2.27 Å)