3HWO

Crystal structure of Escherichia coli enterobactin-specific isochorismate synthase EntC in complex with isochorismate

Summary for 3HWO

• Entry DOI: 10.2210/pdb3hwo/pdb
• Related: 3BZN
• Descriptor: Isochorismate synthase entC, MAGNESIUM ION, (5S,6S)-5-[(1-carboxyethenyl)oxy]-6-hydroxycyclohexa-1,3-diene-1-carboxylic acid, ... (4 entities in total)
• Functional Keywords: isochorismate synthase, entc, chorismate-utilizing enzymes, siderophore, enterobactin, enterobactin biosynthesis, ion transport, iron, iron transport, isomerase, transport
• Biological source: Escherichia coli
• Total number of polymer chains: 2
• Total formula weight: 87067.08

Authors

Sridharan, S.,Blundell, T.L. (deposition date: 2009-06-18, release date: 2010-02-16, Last modification date: 2024-02-21)

• Primary citation: Sridharan, S.,Howard, N.,Kerbarh, O.,Blaszczyk, M.,Abell, C.,Blundell, T.L.; Crystal Structure of Escherichia coli Enterobactin-specific Isochorismate Synthase (EntC) Bound to its Reaction Product Isochorismate: Implications for the Enzyme Mechanism and Differential Activity of Chorismate-utilizing Enzymes; J.Mol.Biol., 397:290-300, 2010; PubMed: 20079748; DOI: 10.1016/j.jmb.2010.01.019

Experimental method

X-RAY DIFFRACTION (2.3 Å)