3HUS
Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
Summary for 3HUS
Entry DOI | 10.2210/pdb3hus/pdb |
Related | 1LT9 1LTJ |
Descriptor | Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, ... (7 entities in total) |
Functional Keywords | fibrinogen fragment d, amyloid, amyloidosis, blood coagulation, disease mutation, disulfide bond, glycoprotein, isopeptide bond, phosphoprotein, secreted, pyrrolidone carboxylic acid, sulfation, blood clotting |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 10 |
Total formula weight | 160847.99 |
Authors | Lord, S.T.,Bowley, S.R.,Okumura, N. (deposition date: 2009-06-15, release date: 2009-08-18, Last modification date: 2023-09-06) |
Primary citation | Bowley, S.R.,Okumura, N.,Lord, S.T. Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions. Biochemistry, 48:8656-8663, 2009 Cited by PubMed: 19650644DOI: 10.1021/bi900239b PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.04 Å) |
Structure validation
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