3HUS
Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D | Fibrinogen alpha chain | polymer | 66 | 7747.0 | 2 | UniProt (P02671) Pfam (PF08702) In PDB | Homo sapiens (human) | Fibrinopeptide A |
| 2 | B, E | Fibrinogen beta chain | polymer | 313 | 35940.2 | 2 | UniProt (P02675) Pfam (PF08702) Pfam (PF00147) In PDB | Homo sapiens (human) | Fibrinopeptide B |
| 3 | C, F | Fibrinogen gamma chain | polymer | 311 | 35233.1 | 2 | UniProt (P02679) Pfam (PF08702) Pfam (PF00147) In PDB | Homo sapiens (human) | |
| 4 | G, H, I, J | Peptide Ligand Gly-Pro-Arg-Pro-amide | polymer | 4 | 426.5 | 4 | |||
| 5 | K, L | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 2 | In PDB GlyTouCan (G21290RB) | |||
| 6 | B, C, E, F | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 7 | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
C, F: 96 - 406 (UniProt: P02679)
| PDB | External Database | Details |
|---|---|---|
| Lys 308 | Asn 334 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 10 |
| Total formula weight | 159546.6 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 1141.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 160848.0 |
