3HUS

Crystal structure of recombinant gamma N308K fibrinogen fragment D with the peptide ligand Gly-Pro-Arg-Pro-amide

3HUS の概要

• エントリーDOI: 10.2210/pdb3hus/pdb
• 関連するPDBエントリー: 1LT9 1LTJ
• 分子名称: Fibrinogen alpha chain, Fibrinogen beta chain, Fibrinogen gamma chain, ... (7 entities in total)
• 機能のキーワード: fibrinogen fragment d, amyloid, amyloidosis, blood coagulation, disease mutation, disulfide bond, glycoprotein, isopeptide bond, phosphoprotein, secreted, pyrrolidone carboxylic acid, sulfation, blood clotting
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 10
• 化学式量合計: 160847.99

構造登録者

Lord, S.T.,Bowley, S.R.,Okumura, N. (登録日: 2009-06-15, 公開日: 2009-08-18, 最終更新日: 2023-09-06)

• 主引用文献: Bowley, S.R.,Okumura, N.,Lord, S.T.; Impaired protofibril formation in fibrinogen gammaN308K is due to altered D:D and "A:a" interactions.; Biochemistry, 48:8656-8663, 2009; PubMed: 19650644; DOI: 10.1021/bi900239b

実験手法

X-RAY DIFFRACTION (3.04 Å)