3HUM

Crystal structure of Penicillin binding protein 4 from Staphylococcus aureus COL in complex with Cefotaxime

3HUM の概要

• エントリーDOI: 10.2210/pdb3hum/pdb
• 分子名称: Penicillin-binding protein 4, (2R)-2-[(1R)-1-({[(2R)-2-amino-2,3-dihydro-1,3-thiazol-4-yl](methoxyimino)acetyl}amino)-2-oxoethyl]-5-methyl-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid (3 entities in total)
• 機能のキーワード: penicillin binding protein 4, cefotaxime, beta-lactamase, serine type d-ala, d-ala-carboxypeptidase, antibiotics, hydrolase-antibiotics complex, hydrolase/antibiotics
• 由来する生物種: Staphylococcus aureus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 102160.78

構造登録者

Navratna, V.,Gopal, B. (登録日: 2009-06-15, 公開日: 2009-11-10, 最終更新日: 2023-11-01)

• 主引用文献: Navratna, V.,Nadig, S.,Sood, V.,Prasad, K.,Arakere, G.,Gopal, B.; Molecular basis for the role of Staphylococcus aureus Penicillin Binding Protein 4 in antimicrobial resistance; J.Bacteriol., 2009; PubMed: 19854906; DOI: 10.1128/JB.00822-09

実験手法

X-RAY DIFFRACTION (2.3 Å)